Melanoma and sunless tanner
In this article, we will figure out whether it is possible to use sunless tanner with a history of melanoma
Beautiful skin is an ideal that people strive for constantly, but the parameters of this beauty change regularly. Even at the beginning of the last century, the skin of representatives of the noble estates had to be snow-white, ladies limited their stay in the sun, protected themselves from its rays with umbrellas. The turbulent rhythm of life of the XX century dictated new standards of beauty. A tanned body has become associated with excellent health, success, wealth. Tanning salons have gained popularity, allowing you to get a perfect even tan in a short time.
But in the early 2000s, restrictions or a ban on the use of tanning beds began to be introduced in many countries - this was caused by an increase in the number of oncological diseases. The link between the risk of skin cancer, melanoma, increased pigmentation and exposure to UV rays turned out to be obvious (the activity of solar radiation caused by the destruction of the ozone layer and the effect of short UV radiation in tanning booths).
Oncologists note that not only sunbathers are at risk, but also representatives of professions associated with prolonged exposure to the sun: farmers, merchants, builders, drivers. Also at risk are people with a large number of moles (nevi), white-skinned, poorly tanned, with light or red hair, light eyes, with freckles. Their body, when exposed to ultraviolet light, almost does not produce protective melanin – the skin is damaged much more easily than in dark-skinned and black-haired.
An alternative to staying in the sun and tanning in the solarium were autobronzants (autobronzers). They allow the skin to acquire a beautiful shade, and their use does not require much time – such a tan is called instant.
The components of self-tanning that provide a tanned skin tone are dihydroxyacetone, erythrulose (quite expensive) and their combination. Reflective particles in the composition of some bronzers give the skin a beautiful shade and shimmer, visually slim.
Upon contact with the upper layers of the epidermis, dihydroxyacetone reacts chemically with amino acids of keratin proteins of the skin and forms dark-colored polymers, melanoidins, which lead to a change in skin color comparable to a sun tan. Melanoidins structurally have a certain similarity with skin melanin, but do not have photoprotective properties, so it is also necessary to use sunscreen.
Conclusion: artificial tanning cream can be a safe alternative to tanning, and can be used if there was a history of melanoma or other skin cancer. However, this does not negate the fact that when going outside, it is necessary to apply sunscreen, as well as regularly self-examine and visit a doctor once a year.
By the way, if you have had melanoma and you are looking for a suitable cream for yourself, then pay attention to Mrs C’s Tan. Its creator is a melanoma warrior from the UK, whose mission is "to help EVERYONE achieve that perfect tan without any risk."
But in the early 2000s, restrictions or a ban on the use of tanning beds began to be introduced in many countries - this was caused by an increase in the number of oncological diseases. The link between the risk of skin cancer, melanoma, increased pigmentation and exposure to UV rays turned out to be obvious (the activity of solar radiation caused by the destruction of the ozone layer and the effect of short UV radiation in tanning booths).
Oncologists note that not only sunbathers are at risk, but also representatives of professions associated with prolonged exposure to the sun: farmers, merchants, builders, drivers. Also at risk are people with a large number of moles (nevi), white-skinned, poorly tanned, with light or red hair, light eyes, with freckles. Their body, when exposed to ultraviolet light, almost does not produce protective melanin – the skin is damaged much more easily than in dark-skinned and black-haired.
An alternative to staying in the sun and tanning in the solarium were autobronzants (autobronzers). They allow the skin to acquire a beautiful shade, and their use does not require much time – such a tan is called instant.
The components of self-tanning that provide a tanned skin tone are dihydroxyacetone, erythrulose (quite expensive) and their combination. Reflective particles in the composition of some bronzers give the skin a beautiful shade and shimmer, visually slim.
Upon contact with the upper layers of the epidermis, dihydroxyacetone reacts chemically with amino acids of keratin proteins of the skin and forms dark-colored polymers, melanoidins, which lead to a change in skin color comparable to a sun tan. Melanoidins structurally have a certain similarity with skin melanin, but do not have photoprotective properties, so it is also necessary to use sunscreen.
Conclusion: artificial tanning cream can be a safe alternative to tanning, and can be used if there was a history of melanoma or other skin cancer. However, this does not negate the fact that when going outside, it is necessary to apply sunscreen, as well as regularly self-examine and visit a doctor once a year.
By the way, if you have had melanoma and you are looking for a suitable cream for yourself, then pay attention to Mrs C’s Tan. Its creator is a melanoma warrior from the UK, whose mission is "to help EVERYONE achieve that perfect tan without any risk."
List of literature
- Lomas A., Leonardi-Bee J., Bath-Hextall F. A systematic review of worldwide incidence of nonmelanoma skin cancer. Br J Dermatol 2012; 166: 1069–80.
- Karjalainen S1, Salo H., Teppo L. Basal cell and squamous cell carcinoma of the skin in Finland. Site distribution and patientsurvival. Int J Dermatol. 1989 Sep; 28(7): 445–50.
- Bastiaens MT, Hoefnagel JJ, Bruijn JA et al. Differences in age, site distribution, and sex between nodular and superficial basal cell carcinoma indicate different types of tumors. J Invest Dermatol 1998; 110:880–4.
- Luz FB, Ferron C., Cardoso GP. Surgical treatment of basal cell carcinoma: an algorithm based on the literature. An Bras Dermatol. 2015 May-Jun; 90(3): 377–83.
- Julien Lanoue, Gary Goldenberg. Basal Cell Carcinoma, А Comprehensive Review of Existing and Emerging Nonsurgical Therapies. J Clin Aesthet Dermatol. 2016 May; 9 (5): 26–36.]
- Vijlder, H., Sterenborg, H., Neumann, H., Robinson, D., Haas, E. (2012). Light Fractionation Significantly Improves the Response of Superficial Basal Cell Carcinoma to Aminolaevulinic Acid Photodynamic Therapy: Five-year Follow-up of a Randomized, Prospective Trial. Acta Dermato Venereologica, 92 (6), 641–647. doi: 10.2340/00015555-1448
- Lehmann, P. (2007). Methyl aminolaevulinate?photodynamic therapy: a review of clinical trials in the treatment of actinic keratoses and nonmelanoma skin cancer. British Journal of Dermatology, 156(5), 793–801. doi: 10.1111/j.1365-2133.2007.07833.x.
- Ceilley RI, Del Rosso JQ. Current modalities and new advances in the treatment of basal cell carcinoma. Int J Dermatol. 2006 May; 45(5): 489–98.
- Wysong, A., Aasi, S. Z., Tang, J. Y. (2013). Update on Metastatic Basal Cell Carcinoma: A Summary of Published Cases From 1981 Through 2011. JAMA Dermatology, 149(5), 615.
- Sekulic A, Migden MR, Basset-Seguin N., Garbe C., Gesierich A., Lao CD., Miller C., Mortier L., Murrell DF., Hamid O., Quevedo JF., Hou J., McKenna E., Dimier N., Williams S., Schadendorf D., Hauschild A.; ERIVANCE BCC Investigators.Long-term safety and efficacy of vismodegib in patients with advanced basal cell carcinoma: finalupdate of the pivotal ERIVANCE BCC study. BMC Cancer. 2017 May 16; 17(1):3 32. doi: 10.1186/s12885-017-3286-5.
- Lear JT., Migden MR., Lewis KD., Chang ALS., Guminski A., Gutzmer R., Dirix L., Combemale P., Stratigos A., Plummer R., Castro H, Yi T., Mone M., Zhou J., Trefzer U., Kaatz M., Loquai C., Kudchadkar R., Sellami D., Dummer R. Long-term efficacy and safety of sonidegib in patients with locally advanced and metastatic basal cell carcinoma: 30-month analysis of the randomized phase 2 BOLT study.J Eur Acad Dermatol Venereol. 2018 Mar; 32 (3): 372–381. doi: 10.1111/jdv.14542. Epub 2017 Nov 6.
- Wieman TJ., Shively EH., Woodcock TM. Responsiveness of metastatic basal-cell carcinoma to chemotherapy. A case report. Cancer. N1983; 52 (9): 1583–1585.
- Coker DD, Elias EG, Viravathana T, et al. Chemotherapy for metastatic basal cell carcinoma. Arch Dermatol. 1983; 119 (1): 44–50.
- Guthrie TH., Jr, McElveen LJ., Porubsky ES., Harmon JD. Cisplatin and doxorubicin. An effective chemotherapy combination in the treatment of advanced basal cell and squamous carcinoma of the skin. Cancer. 1985; 55 (8): 1629–1632.
- Bason MM., Grant-Kels JM., Govil M. Metastatic basal cell carcinoma: response to chemotherapy. J Am Acad Dermatol. 1990; 22 (5 Pt 2): 905–908.
- Khandekar JD. Complete response of metastatic basal cell carcinoma to cisplatin chemotherapy: a report of two patients. Arch Dermatol. 1990; 126 (12): 1,660.
- Denic S. Preoperative treatment of advanced skin carcinoma with cisplatin and bleomycin. Am J Clin Oncol. 1999; 22 (1): 32–34.
- Jefford M., Kiffer JD., Somers G., et al. Metastatic basal cell carcinoma: rapid symptomatic response to cisplatin and paclitaxel. ANZ J Surg. 2004; 74 (8): 704–705.
- Moeholt K., Aagaard H., Pfeiffer P., Hansen O. Platinum-based cytotoxic therapy in basal cell carcinoma-a review of the literature. Acta Oncol. 1996; 35 (6): 677–682.
- Carneiro BA., Watkin WG., Mehta UK., Brockstein BE. Metastatic basal cell carcinoma: complete response to chemotherapy and associated pure red cell aplasia. Cancer Invest. 2006; 24 (4): 396–400.